FRAMELEGEND
(02) (Warframe) © 2026

Nidus Prime

Mutation is endless. The ravening plague-bearer returns in a long-unseen form, seething with a primal strain of the Infestation.

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Nidus Prime

(Base stats)

Health
825
Shield
0
Armor
425
Energy
140
Sprint
1
Mastery
0

Values at max rank as reported by the game export · snapshot 30 Sept 2026

(Where it sits)

Across the 119 frames in the roster, Nidus Prime sits in the top fifteen per cent for health (6th of 119) and armor (12th of 119).

It is thin on shield (119th of 119) and energy (91th of 119), which is what a build has to answer for.

It ships with 3 polarities already installed, plus Madurai on the aura slot, so that much of the board costs no forma.

(Loadout facts)

Pre-installed polarities
MaduraiNaramonVazarin
Aura slot
Madurai
Progenitor element
Toxin
Role
Damage · Survival · Crowd Control
Introduced
30.7

(Passive)

If Nidus is killed with at least _ stacks of Mutation, those _ stacks are consumed; this grants _s of invulnerability and restores Health to _%.

(Abilities)

  1. 01

    Virulence 40 energy

    Rupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.

    Augment: Teeming Virulence

  2. 02

    Larva 25 energy Subsumable

    Spawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.

    Augment: Larva Burst

  3. 03

    Parasitic Link 25 energy

    Bind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength and Weapon Damage increased. Linked enemies take some of the damage inflicted on Nidus.

    Augment: Parasitic Vitality

  4. 04

    Ravenous 3 mutation stacks

    Gluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.

    Augment: Insatiable

Costs are base figures, before efficiency.

How to get Nidus Prime

Nidus Prime comes out of Void relics — 26 of them across its 4 parts. It is in the Vault: those relics no longer drop, so the only routes left are a player who already holds them and the occasional unvaulting.

In the Vault — the relics below are not in the current drop tables.

Blueprint

RelicIntactIntExceptionalExcFlawlessFlaRadiantRad
Lith K1011%13%17%20%
Lith R211%13%17%20%
Lith S1711%13%17%20%
Lith T911%13%17%20%
Meso N1211%13%17%20%
Meso P811%13%17%20%
Meso R511%13%17%20%
Axi A1411%13%17%20%

Chassis

RelicIntactIntExceptionalExcFlawlessFlaRadiantRad
Lith N122%4%6%10%
Lith N72%4%6%10%
Meso N132%4%6%10%
Meso N142%4%6%10%
Neo N182%4%6%10%
Axi N122%4%6%10%

Neuroptics

RelicIntactIntExceptionalExcFlawlessFlaRadiantRad
Neo N162%4%6%10%
Neo S1911%13%17%20%
Axi N102%4%6%10%
Axi N92%4%6%10%

Systems

RelicIntactIntExceptionalExcFlawlessFlaRadiantRad
Meso A325.33%23.33%20%16.67%
Meso B525.33%23.33%20%16.67%
Meso D725.33%23.33%20%16.67%
Meso H225.33%23.33%20%16.67%
Meso P925.33%23.33%20%16.67%
Neo A825.33%23.33%20%16.67%
Neo C225.33%23.33%20%16.67%
Neo N1925.33%23.33%20%16.67%

Chances are per reward roll, as the drop tables state them. Relic rows show the chance at each refinement; a relic drops Intact.

How to craft Nidus Prime

Credits, all in
70,000
Build time
3 days 12 hours
Rush, all in
125 p

Build time assumes the 3 components build at the same time in separate foundry slots — 12 hours for the slowest, then 3 days for the frame itself. One slot at a time comes to 4 days 12 hours.

Everything it eats

  • 5,500Alloy PlateVenus · Phobos · Ceres · Jupiter · Pluto · Sedna · Zariman Ten Zero
  • 4,975Nano SporesDeimos · Saturn · Neptune · Eris
  • 3,800SalvageMars · Jupiter · Sedna · Kuva Fortress
  • 1,425Polymer BundleMercury · Venus · Uranus
  • 1,250RubedoEarth · Phobos · Europa · Pluto · Sedna · Void · Lua
  • 1,100CircuitsVenus · Ceres · Kuva Fortress
  • 600CryoticExcavation Missions on Venus, Earth, Phobos, Europa, and Neptune
  • 450PlastidsPhobos · Saturn · Uranus · Pluto · Eris
  • 5Orokin CellDeimos · Ceres · Saturn
  • 3NeurodesEarth · Deimos · Eris · Lua
  • 2Argon CrystalVoid
  • 2Nitain ExtractNightwave Cred Offerings
  • 2TelluriumArchwing Missions on Uranus

Under each resource, the planets whose missions drop it — or, where no planet does, how it is found, as the WARFRAME Wiki records it.

The tree

Nidus Prime blueprint25,000 cr · 3 days · rush 50 p
  • 1 Prime Neuroptics · 15,000 cr · 12 hours
  • 1 Prime Chassis · 15,000 cr · 12 hours
  • 1 Prime Systems · 15,000 cr · 12 hours
  • 5 Orokin Cell
Prime Neuroptics15,000 cr · 12 hours
  • 2 Argon Crystal
  • 600 Cryotic
  • 1,100 Circuits
  • 4,975 Nano Spores
Prime Chassis15,000 cr · 12 hours
  • 2 Tellurium
  • 450 Plastids
  • 1,425 Polymer Bundle
  • 5,500 Alloy Plate
Prime Systems15,000 cr · 12 hours
  • 2 Nitain Extract
  • 3 Neurodes
  • 1,250 Rubedo
  • 3,800 Salvage

(Builds)

No FrameLegend build for Nidus Prime yet — see what players have published →

(Sources)

Stats, ability text and art come from the game export. Polarities, ability costs, augments, subsume status and the crafting recipes come from the WARFRAME Wiki, CC BY-SA. Every figure, ranking and total on this page is computed from our own dataset.